Compatibility: Warning! These parts have potential issues or incompatibilities. See details below.
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Potential Issues / Incompatibilities
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A
Warning: The Asus PRIME B650-PLUS ATX AM5 Motherboard supports the AMD Ryzen 9 9900X 4.4 GHz 12-Core Processor with BIOS version 2613. If the motherboard is using an older BIOS version, updating the BIOS will be necessary to support the CPU.
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B
Note: Fan compatibility checking is currently not supported.
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C
Note: The video card PCIe 16-pin power connector adapter is being supplied by three 6+2-pin power connectors. Please ensure that the three 6+2-pin power connectors are not daisy-chained and do not share the same power cable.
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D
Disclaimer: Some physical constraints are not checked, such as RAM clearance with CPU Coolers.
Motherboard Usage

Asus PRIME B650-PLUS ATX AM5
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CPU Sockets
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CPU_1
AM5
CPU_1 (AM5)
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Memory Slots
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RAM_1
DDR5 288-pin DIMM
RAM_1 (288-pin DIMM)
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RAM_2
DDR5 288-pin DIMM
RAM_2 (288-pin DIMM)
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RAM_3
DDR5 288-pin DIMM
RAM_3 (288-pin DIMM)
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RAM_4
DDR5 288-pin DIMM
RAM_4 (288-pin DIMM)
* Refer to the motherboard manual to determine which specific memory slots to use.
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M.2 Slots
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M2_1
M.2 2242/2260/2280/22110
M-key
M2_1 (M)
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M2_2
M.2 2242/2260/2280/22110
M-key
M2_2 (M)
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M2_3
M.2 2230
E-key
M2_3 (E)
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Expansion Slots
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PCIE_1
PCIe 4.0 x16
PCIE_1 (x16)
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Covered
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PCIE_2
PCIe 4.0 x1
PCIE_2 (x1) Covered
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PCIE_3
PCIe 4.0 x16 (@x4)
PCIE_3 (x16 @x4) Covered
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PCIE_4
PCIe 4.0 x1
PCIE_4 (x1)
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SATA Ports
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SATA_1
SATA 6.0 Gb/s
SATA_1 (6.0 Gb/s)
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SATA_2
SATA 6.0 Gb/s
SATA_2 (6.0 Gb/s)
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SATA_3
SATA 6.0 Gb/s
SATA_3 (6.0 Gb/s)
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SATA_4
SATA 6.0 Gb/s
SATA_4 (6.0 Gb/s)
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USB Headers
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USB_1
USB 2.0 Header
USB_1 (2.0)
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USB_2
USB 2.0 Header
USB_2 (2.0)
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USB_3
USB 3.2 Gen 1 Header
USB_3 (3.2 Gen 1)
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NZXT H6 Flow ATX Mid Tower (USB 3.2 Gen 1 Header Plug)
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USB_4
USB 3.2 Gen 2 Header
USB_4 (3.2 Gen 2)
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NZXT H6 Flow ATX Mid Tower (USB 3.2 Gen 2 Header Plug)
Power Supply Connector Usage

NZXT C1000 (2022) 1000 W 80+ Gold Certified Fully Modular ATX
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Motherboard Power Connectors
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ATX24_1
24-pin ATX
ATX24_1 (24-Pin)
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Asus PRIME B650-PLUS ATX AM5 (24-pin ATX)
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EPS_1
8-pin EPS
EPS_1 (8-Pin)
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Asus PRIME B650-PLUS ATX AM5 (8-pin EPS)
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EPS_2
8-pin EPS
EPS_2 (8-Pin)
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PCIe Power Connectors
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PCIE_1
6+2-pin PCIe
PCIE_1 (6+2-Pin)
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PNY XLR8 Gaming VERTO EPIC-X RGB OC GeForce RTX 4080 SUPER 16 GB (PCIe 12+4-pin 12VHPWR #1)
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PCIE_2
6+2-pin PCIe
PCIE_2 (6+2-Pin)
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PNY XLR8 Gaming VERTO EPIC-X RGB OC GeForce RTX 4080 SUPER 16 GB (PCIe 12+4-pin 12VHPWR #1)
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PCIE_3
6+2-pin PCIe
PCIE_3 (6+2-Pin)
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PNY XLR8 Gaming VERTO EPIC-X RGB OC GeForce RTX 4080 SUPER 16 GB (PCIe 12+4-pin 12VHPWR #1)
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PCIE_4
6+2-pin PCIe
PCIE_4 (6+2-Pin)
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PCIE_5
6+2-pin PCIe
PCIE_5 (6+2-Pin)
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PCIE_6
6+2-pin PCIe
PCIE_6 (6+2-Pin)
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SATA Power Connectors
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SATA_PWR_1
SATA
SATA_PWR_1
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SATA_PWR_2
SATA
SATA_PWR_2
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SATA_PWR_3
SATA
SATA_PWR_3
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SATA_PWR_4
SATA
SATA_PWR_4
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SATA_PWR_5
SATA
SATA_PWR_5
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SATA_PWR_6
SATA
SATA_PWR_6
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Molex Power Connectors
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MOLEX_1
4-pin AMP/Molex
MOLEX_1
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MOLEX_2
4-pin AMP/Molex
MOLEX_2
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MOLEX_3
4-pin AMP/Molex
MOLEX_3
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MOLEX_4
4-pin AMP/Molex
MOLEX_4
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MOLEX_5
4-pin AMP/Molex
MOLEX_5
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MOLEX_6
4-pin AMP/Molex
MOLEX_6
Case Drive Bay Usage

NZXT H6 Flow ATX Mid Tower
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Drive Bays
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INT_3
Internal 3.5"
INT_3 (3.5")
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INT_1
Internal 2.5"
INT_1 (2.5")
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INT_2
Internal 2.5"
INT_2 (2.5")

















