So, I work from home, as a software developer, so I typically do the code -> compile -> test cycle, and often use containers and VMs as part of my development. Hence LOTS of RAM, and a fast processor (single thread) was needed. Also, hangouts EATS cpu, and as I work remotely and all my conversations are on hangouts, I needed something that could keep up with that.
The ARCTIC Freezer 240 is pretty much silent in the Fractal Design S, so that worked really well. And that's on full load. I've not overclocked (yet) and might not, as this thing has enough power for me and is quiet.
The RX 480 on the other had is very, very, noisy under full load. I've undervolted it, knocked a few kHz off the performance, and slowed the fans down to make it acceptable. I'll change the card for something else (maybe Vega if it's any good) in the future.
I could've gone Ryzen, and seriously thought about it; however, I wanted a known solution, with excellent stability and good performance. The 'old' X99 + 6800K gives me that, and it will still be a good machine for several years. (and yes, that's probably confirmation bias after the fact to justify my purchase decisions!).